Here’s a really cool paper:
They show that temperature-dependent sex determination (or rather, in this case, trans-differentiation) is mediated by the methylation of the aromatase promoter. An obvious question is whether the environmentally driven methylation of the promoters of genes involved in sexual differentiation could be a general mechanism in species with environmental sex determination. I am sure lots of people will be asking this soon, at least in vertebrates.
Does anyone known a dipteran with temperature-dependent sex determination? Can’t think of one right now.