Author: akopp Page 7 of 15
Hey Everyone,
WCB will be held at 4:00PM-5:00PM Friday, July 27th. The paper we will be discussing (Venken et al 2011) outlines the MIMIC lines a exciting new transgenic resource. The link is below: http://www.nature.com/nmeth/journal/v8/n9/full/nmeth.1662.html
Really interesting story coming out of the Heliconius genome:
Butterfly genome reveals promiscuous exchange of mimicry adaptations among species
A few months ago, we had a little seat-of-the-pants discussion of the (macro)evolution of CNS and sensory systems in arthropods. If you want to follow up on that, here is a little review:
Hey everybody, the first summer meeting of the WCB club is this Friday, 4-5 pm. Artyom will talk about the following paper:
Fluorescent fusion protein knockout mediated by anti-GFP nanobody
As many in our lab know, identifying homologous/orthologous genes in sister species is tedious process that even with decades of research, still generates vast uncertainty, which in turn, confounds downstream analyses (and is a pain to be honest).
Here are two recent papers that try to address the issue:
Domain enhanced lookup time accelerated BLAST
Prediction of Protein Domain with mRMR Feature Selection and Analysis
Another review in the last issue of NRG. Mainly human/primate work.
“Focusing on work in primates, the authors discuss the evolution of gene expression, ways of exploring mechanisms that underlie expression changes and complementary work in model organisms on the functional effects of expression changes.”
A useful review in NRG. Includes an overview of different bioinformatic and experimental approaches, and a list of useful software and websites.
For some reason, everyone really likes Dave’s work on hydras. Here are the recent articles:
Hydra “see” the light – but they don’t have eyes